Lakers vs. Pistons NBA expert prediction and odds for Wednesday, Nov. 29

Betting odds, pick and prediction for the Los Angeles Lakers' matchup with the Detroit Pistons.

Los Angeles Lakers forward LeBron James (6) controls the ball.
Los Angeles Lakers forward LeBron James (6) controls the ball. / David Reginek-USA TODAY Sports

The Los Angeles Lakers suffered an embarrassing loss against the Philadelphia 76ers on Monday, but they have the ultimate bounce-back spot on Wednesday night against the Detroit Pistons.

Detroit is a dumpster fire right now, losing 14 straight games to fall to 2-15 on the season. Even with Cade Cunningham healthy, the Pistons simply don’t have the right pieces to be a winning team this season. 

The Lakers, who have listed superstar LeBron James as questionable for this game, are 10-8 on the season and a troubling 4-5 against the spread on the road. Does that change on Wednesday night? 

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Lakers vs. Pistons odds, spread and total

Lakers vs. Pistons how to watch

  • Date: Wednesday, Nov. 29
  • Game Time: 7:00 p.m. EST
  • Venue: Little Caesars Arena
  • How to Watch (TV): Spectrum SportsNet, Bally Sports Detroit
  • Lakers Record: 10-8
  • Pistons Record: 2-15

Lakers vs. Pistons injury reports

Lakers injury report

  • Anthony Davis – probable
  • LeBron James – questionable
  • Rui Hachimura – out
  • Cam Reddish – probable
  • Jarred Vanderbilt – out
  • Gabe Vincent – out

Pistons injury report

  • Monte Morris – out
  • Bojan Bogdanovic – out
  • Joe Harris – out
  • Malcolm Cazalon – out
  • Jared Rhoden – out
  • Stanley Umude – out

Lakers vs. Pistons key players to watch

Los Angeles Lakers

Anthony Davis: There is a key trend with the Lakers and Davis, and the team needs him to step up against an inferior Detroit team tonight. In the games that Davis has scored 20 or more points this season, the Lakers are 7-2. The games he hasn’t? Los Angeles is a combined 3-6. 

AD should be able to dominate against the Pistons frontcourt on Wednesday. 

Detroit Pistons

Ausar Thompson: Rookie Ausar Thompson has been a lone bright spot for the Pistons this season, averaging 11.4 points and 9.5 rebounds per game. He could draw the assignment on LeBron James in this game. 

Lakers vs. Pistons prediction and pick

Detroit hasn’t just been bad at winning games this season. 

The team is just 7-10 against the spread, despite the fact that it has found itself as a sizable underdog on many occasions. The Pistons are losing games by an average margin of 8.1 points this season. 

That’s good news for the Lakers, who are just seven-point favorites on the road in this matchup. 

These two teams are both in the bottom five in the NBA in offensive rating this season, but the Lakers are a much better team on defense, ranking 14th in defensive rating compared to Detroit (23rd). 

James was vocal about things needing to change after Monday's loss, and I wouldn’t be shocked to see the four-time champion walk the walk on Wednesday night with a big showing. 

I cannot trust the Pistons, so let’s take the Lakers to cover in what could be a lower-scoring matchup. 

Game odds refresh periodically and are subject to change.

Find Peter Dewey's NBA betting record here (futures included). You can also follow my daily plays on BetStamp here.